HMS Indus was an 80-gun two-deck second-rate ship of the line of the Royal Navy, launched on 16 March 1839 at Portsmouth Dockyard.

[1] The design of Indus was based upon the Danish Christian VII, captured during the Second Battle of Copenhagen.

Captain John Charles Dalrymple Hay had her until 25 November 1856, during which time she served as Rear-Admiral Houston Stewart's flagship, based at Devonport.

Captain William King-Hall was her next commander, and she continued to serve as Houston Stewart's flagship, now on the North American and West Indian stations.

In 1860 Indus was converted to serve as a guardship.