Captain Henry Lambert commissioned Iphigenia and on 28 January 1809 sailed her to the Cape of Good Hope and Bombay.
On 13 September she was at Bombay where her crew helped fight, albeit unsuccessfully, the fire on Shah Ardaseer.
The squadron blockaded Isle de France from May, and started operations to attempt a take-over on 7 July 1810.
On 10 August, the squadron, under Samuel Pym, landed parties to capture the Île de la Passe and take control of Port-Impérial, initiating the Battle of Grand Port.
The French had moved the buoys marking the passage through the reef, causing Magicienne and Sirius to run aground and leading the British to scuttle them by fire.
After exchanging broadsides and small arms fire for half an hour, during which the French had the upper hand, the British attempted a boarding.
All Africaine's officers had been killed or wounded in the action, save for Colonel Barry, and only 69 men were uninjured.
[3] After fitting out at Portsmouth from November to February 1812, Iphigenia was recommissioned in January under Captain Lucius Curtis.
[3] On 17 April 1814, a British squadron consisting of Furieuse, Aboukir, Iphigenia, Swallow and Cephalus supported the successful assault on Genoa.
On 15 April, her boats captured six slave ships on the Bonny River: Vigilante, Petite Betsey, Ursule, the Spanish Yeanam, Becaa, and the French brigantine Utile.
On 27 August her barge, under the command of Lieutenant Stokes, in company with Zephyr, Harrison, which was on her way from Jamaica to London, captured a pirate schooner of about 250 tons (bm), six 18-pounder guns, and 60 men.
[11] "The Commissioners for executing the office of Lord High Admiral of the United Kingdom of Great Britain and Ireland" offered Iphigenia for sale at Woolwich on 19 February 1850.