HMS Medusa (A353) (formerly HDML 1387) is a harbour defence motor launch of the Royal Navy that saw service in World War II, constructed by Newman, R A & Sons Ltd, Poole in 1943.

[1][2][3] HDML 1387 took part in exercise Fabius 1 in May 1944, which consisted of practise amphibious landings at Slapton Sands, Devon.

[1][4][3][6] After World War II, she received a refit and was converted into a Fast Despatch Boat, being renamed FDB 76.

[1][7] Medusa was paid off on 30 November 1965 at Devonport, sustaining damage from a fire that started on the final day of her service in the Royal Navy.

Medusa has been present at events such as the Fleet Review marking the 200th anniversary of the Battle of Trafalgar in 2005, and the Diamond Jubilee Pageant in 2012.