The privateer General Augereau had captured her on 4 August in a notable single ship action.

[3] On 12 September Nautilus detained the American ship Colombe, of Boston, Iday, master.

[4] On 12 November Nautilus detained the Spanish ship Echo, Francisco Barzelo, master.

Before he left he sent into Plymouth a valuable Spanish ship from the River Plate that arrived on 23 February.

[8] After the Battle of Trafalgar on 21 October, Lt. Lapenotiere in HMS Pickle raced Captain Sykes in Nautilus over 1000 miles to England with the news of the victory.

In the early morning of 4 May 1806, the boats of HMS Renommee and Nautilus, under the command of Lieutenant Sir William Parker, of Renommee, brought out from under the fire of the guns of the town and tower of Vieja and also from under the fire of more than 100 musketeers, the Spanish naval schooner Giganta.

Captain Sir Thomas Livingstone, of Renommee, recommended that the Navy take Giganta into service at Gibraltar.

Nautilus left the Bay of Abydos, in the Hellespont, with urgent despatches for the Commander-in-chief off Cadiz.