HMS Pembroke was a 60-gun fourth rate ship of the line of the Royal Navy, designed by Sir Joseph Allin and built by Thomas Bucknall at Plymouth Dockyard to the draught specified in the 1745 Establishment as amended in 1752, and launched on 2 June 1757.

When the elder Simcoe died in 1759 he was replaced by John Wheelock who served as captain for the remaining seventeen years of Pembroke's active service.

[2] Thomas Bisset served as ships master during her commissioning, then responsibility passed to James Cook, who would later become the first European to reach the eastern Australian coastline.

[2] Pembroke saw service in the North American theatre of the Seven Years' War, including the Siege of Louisbourg under Captain Simcoe, and the Capture of Québec under Captain Wheelock, both with James Cook as master.

In advance of the latter battle, the ship played an important role charting the approaches to Québec up the St. Lawrence River, so that the main fleet could follow.