HMS Tweed was a 32-gun sailing frigate of the fifth rate produced for the Royal Navy.

She was designed in 1757 by Sir Thomas Slade, based on the lines of the smaller sixth rate HMS Tartar, but with a 10-foot midsection inserted.

On 15 March 1761 Tweed captured the French privateer Hardi, off Cape Finisterre.

[2] In 1763 command passed to Captain Charles Douglas until Tweed paid off into reserve in April 1765.

The design was not considered to be very successful and no further ships of this class were built, while the Tweed herself was sold in 1776 following a survey in 1771 that indicated that she would require a Middling Repair taking £3,500 and nine months to complete.