Wolverine was one of eight destroyers deployed by Rear Admiral Ernest Troubridge to assist his squadron of Armoured cruisers in stopping the German ships escaping to Austrian waters.

[18][19][20] On 1 November 1914 she and the destroyer Scorpion sank a Turkish armed yacht, believed to be involved in minelaying operations, in the Gulf of Smyrna.

[22] During the initial landings at ANZAC Cove and at Cape Helles, Wolverine joined several other destroyers in minesweeping operations in the Dardanelles straits to allow Allied battleships to bombard Turkish positions.

Despite these patrols, the Turkish destroyer Muavenet-i Milliye managed to sneak past Beagle and Bulldog on the northern side of the straits and torpedoed and sunk Goliath before successfully escaping.

[26] On 28 June Wolverine provided support for the advancing forces at the Battle of Gully Ravine, helping to break up a Turkish counter attack.

[30] Wolverine was recalled to home waters and assigned to the 2nd Destroyer Flotilla now based at Buncrana, near Lough Swilly in the north of Ireland in October 1917.

[31][32] On 12 December 1917, Wolverine was part of an escort group on the way to rendezvous with a Britain-bound Atlantic convoy off the northwest coast of Ireland, when the force's senior officer, aboard Hardy ordered a course change.

After carrying out the manoeuvre, Wolverine was rammed by the fleet sweeping sloop Rosemary, with the destroyer rolling over and sinking as a result of the damage received.