5580615460ENSG00000168453ENSMUSG00000022096O43593Q61645NM_005144NM_018411NM_021877NM_001379479NP_005135NP_060881NP_068677NP_001366408HR is a gene encoding Protein hairless.

[5][6][7] This gene encodes a protein whose function has been linked to hair growth.

A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases.

[7] Variations in this gene are involved in low levels of hair (baldness / alopecia / hypotrichosis)[8] Mutations in this gene in humans have been documented in cases of autosomal recessive congenital alopecia[9] and atrichia with papular lesions.

[10][11] [12] [13] [14] The protein contains a Zinc finger domain.