2DIT2733672459ENSG00000102241ENSMUSG00000067873O43719Q8BGC0NM_001163280NM_014500NM_028242NM_029371NP_001156752NP_055315NP_082518NP_083647HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene.

[5][6] Whereas most DNA sequence-specific transcription factors increase the rate of initiation and interact with enhancer or promoter DNA, human immunodeficiency virus-1 (HIV-1) Tat predominantly stimulates elongation and interacts with the trans-acting responsive (TAR) RNA element.

[6] HTATSF1 has also been shown to be involved in intron retention, and is associated with splicing of mRNAs that encode ribosomal proteins.

[7] It is also associated with a naïve pluripotent state, although the relationship is complex and is strongly affected by other pluripotency factors such as Nanog and KLF2.

This article on a gene on the human X chromosome and/or its associated protein is a stub.