Hackleburg is a town in Marion County, Alabama, United States.

Hackleburg developed in the early 19th century as a stop along Jackson's Military Road.

It was named by the early drovers of sheep who passed through the region while en route to market in Tuscumbia, and whose sheep encountered a thorny plant growing in abundance in that area and known locally by the name hack burrs (often corrupted to "hack berries") and which same plants were often fatal to sheep, besides being destructive to their wool.

[3] Hackleburg incorporated in 1909 following the construction of a branch line of the Illinois Central Railroad through the area.

[3] Hackleburg marks the highest point (some 931 feet above sea level) along the route connecting Miami, Florida with Chicago, Illinois.

[4] On April 27, 2011, Hackleburg suffered catastrophic damage when it was hit by an EF5 tornado – part of the 2011 Super Outbreak.

[7] Many people rebuilt here, although 2017 population estimates showed a slight decline from 2010.

Dismals Canyon, a National Natural Landmark, is located 4 miles (6 km) northeast of Hackleburg.

[1] The town center is on the Tennessee Valley Divide (watershed), with half of the town draining north toward Bear Creek, a tributary of the Tennessee River, and half draining south to tributaries of Clifty Creek, part of the Tombigbee River basin.

As of the 2020 United States census, there were 1,425 people, 536 households, and 344 families residing in the town.

The Marion County Board of Education initiated construction of a $25 million total K-12 academic complex in Hackleburg.

The 2007 Hackleburg High School baseball team won the 1A State Championship in the Alabama High School Athletic Association state baseball tournament.