As the first Secretary of the Woman's Auxiliary of the Presbyterian Church, U.S., she worked for civil rights and interracial cooperation, especially in the American South.

[10] She resigned from the national secretary position in 1929, for health reasons, but remained involved in the programs she helped to launch for ten further years.

[3] Beyond church settings, Winsborough was active in the Commission on Interracial Cooperation (CIC), and was a founding member of the Association of Southern Women for the Prevention of Lynching (ASWPL).

[3][4][15][16] Winsborough Hall, the first women's dormitory at Stillman College, was named in her memory,[17] as was a building at Montreat Conference Center in North Carolina.

[20] Her granddaughter and namesake, Hallie Paxson Davis Christian, was an engineer, and an ordained Methodist minister.