At the 8th General Assembly of the ARF party that took place in Karin in 1914, he was strongly opposed to any cooperation with the Young Turks,[1] and largely supported an alliance with the Russian Empire.

[2] At the beginning of the First World War, Hamazasp participated in the Caucasus Campaign and was appointed Commander of the 3rd Armenian volunteer battalion.

After the February Revolution in 1917, Hamazasp was appointed the military police commander of Alashkert, until Russian troops left the Caucasian front.

[4] He displayed his abilities as an experienced strategist and organizer, playing a decisive role in the operations of Ganja and Yevlakh and for 4 months fought against overwhelming Turkish forces of the Army of Islam.

[1] In the autumn of 1918, after the defeat of Turkey in the First World War, Hamazasp came back to Armenia and was appointed military commander of the region of Nor Bayazet.