The county and the Morristown MSA are included in the Knoxville-Morristown-Sevierville, TN Combined Statistical Area.

Governor Dewitt Clinton Senter, a resident of the county, used his influence to assist in its establishment.

Edward R. Talley and Calvin Ward both earned them while fighting on the Western Front.

[9] During World War II, the attack transport naval ship USS Hamblen was named after the county.

The main source of water on Hamblen County is the man-made Cherokee Lake.

Cherokee Lake was created during WWII as part of the TVA hydroelectric project.

The lake is fed by multiple sources, including a series of natural creeks and runoff waters.

In total, Cherokee Lake has 28,780 acres of surface area and extends for 400 miles of shoreline, though only a portion of this resides in Hamblen County.

[11] As of the 2020 United States census, there were 64,499 people, 24,456 households, and 16,391 families residing in the county.

Several large industrial parks on the eastern, western, and southern parts of the county are home to manufacturing facilities for regionally, nationally, and internationally based corporations.

[34] The current mission statement is, "Partnering with families to provide a Christ-centered and academically challenging education, equipping students with a biblical worldview and a heart for Christ, that they may grow in wisdom, stature and in favor with God and man.

[40] Like almost all of East Tennessee, Hamblen County has long voted overwhelmingly Republican, starting with its powerful Unionist sentiment during the Civil War.