Meddeb partnered with the British company Virgin Cola in 2002 to produce soft drinks for the Tunisian market, but the partnership lasted only four years.

[7] Although Hamdi Meddeb is often invited and met by presidents and prime ministers of Tunisia, he rarely appears in the media or gives interviews.

[8][9] After the collapse of the regime in Tunisia on 14 January 2011, several businessmen and captains of industries were accused of corruption and their support for Zine El Abidine Ben Ali in his 2009 presidential campaign.

[10] Meddeb's friendship with Mohamed Sakher El Materi, Ben Ali's son-in-law, caused many rumors to spread about his reputation as a businessman.

In November 2010, Meddeb and Matri bought a 25 percent stake in Tunisiana (later rebranded as Ooredoo Tunisia).