It was earlier known as Prince of Wales King Edwards Memorial Hospital for Men.

The year 1953 saw further extension in the Hamidia Hospital, when the present building inside the Fort Fatehgath was occupied.

Hamidia Hospital played a crucial role in emergency response and care after the Bhopal disaster.

[citation needed] The latest expansion plan for Hamidia aims to create a state-of-the-art multi-speciality "Smart Medi-City" with 2000 beds, a medical college with the intake of 250, and residential quarters for the staff.

Designed as a LEED Platinum Green rated complex, Hamidia overlooks the magnificent Grand Lake and has been designed around several notable historical and religious buildings within this precinct, all of which are integral to the urban fabric of the area.