During this period, which formed the first decade of her career, many of her songs became hits, including "Yalanın Batsın", "Sen Yoluna... Ben Yoluma...", "Acele Etme", "Kırmızı", "Kelepçe", "Aşkın Ateşi", "Kibir" and "Romeo".

Although Yener's electronic songs received critical praise, she suffered commercial loss compared to her previous works, which resulted in several problems with her producing partners, causing a change in the production company and label twice.

[17][18] Various Turkish newspapers started making predictions about the outcome of her collaboration with Altan Çetin, a well-known songwriter who had previously worked with İzel.

[30] Yener also appeared in the album Türk Marşları, prepared by Gendarmerie General Command together with Turkish pop singers and released at the end of 2000.

[42] During that period, Yener played in the commercials for Filli Boya in June 2002,[43] and in July presented one episode of the TV program Pazar Keyfi.

[47] Yener's third studio album was recorded in Hamburg and Istanbul, and was released under the title Aşk Kadın Ruhundan Anlamıyor in July 2004 by Erol Köse Production.

[50] The hit songs "Acele Etme", "Kırmızı" and "Acı Veriyor" were all turned into music videos, followed by separate clips for "Armağan", "Hoşgeldiniz" and "Bu Yüzden".

[69][70] The song "Kibir (Yanmam Lazım)", written and composed by Sezen Aksu, was chosen as the album's lead single and a music video was released for it.

"[77] Yener's definition of grocery music to describe the songs that she found to be of poor quality came with responses from various people including Akalın, Bengü and Ortaç.

As a result of further disputes, she terminated the album contract with the company by paying compensation, so that she left Erol Köse Production in a controversial manner.

[107] Hande Yener's announcement at the end of 2009 that she would make pop music again created a sensation in the Turkish press and caused critics to question the decision.

[122] In April 2011, Yener appeared as the featured artist on two of Sinan Akçıl's songs from the album Kalp Sesi: "Atma" and "Söndürülmez İstanbul".

[139][140] In November 2013, Yener's mutual single with Volga Tamöz, "Biri Var" was released on Deezer, on the day the service celebrated its launch in Turkey.

[141] From 5 October to 17 November 2013, Yener appeared as a judge on ATV's music contest Veliaht, which ended after 6 weeks due to low ratings.

Yener's eleventh studio album Mükemmel was released by Poll Production in June 2014, and sold 50,000 copies in Turkey by the end of the year.

[146][147] After three months of preparations, on 25 August Yener performed at Harbiye's Cemil Topuzlu Open-Air Theatre, and Berksan, Mehmet Erdem and David Vendetta also made appearances on the stage.

[159] The singer continued her musical career by publishing "Kışkışşş", inspired by a scene in the movie Sosyete Şaban (1985), and made a duet with Serdar Ortaç on the song "İki Deli".

Güngör was later caught by police in front of Yener's house and according to the Constitution of Turkey was charged with "sexual harassment and disrupting the peace and tranquility of individuals".

[163] As a result of the trial, the court decided that Güngör, who was diagnosed with atypical psychosis, had no criminal responsibility as he was not able to perceive the legal meaning and consequences of the alleged offenses.

[182] By the end of the year, Yener and fellow singer Demet Akalın reconciled after an 11-year feud which made them the subject of many tabloid news.

Many singers and songwriters collaborated with Yener on this album, including Berksan, Devrim Karaoğlu, Mete Özgencil, Fikri Karayel, and Misha.

[2][196] Dilmener also mentioned that "after the 90s stars such as Yonca Evcimik, Aşkın Nur Yengi, Asya, and İzel faced a decline in their career in the 2000s, Yener made an ostentatious debut in [Turkey's] music markets and moved herself to the top with songs such as 'Kırmızı' and 'Acele Etme' which were written by Altan Çetin."

Dilmener's viewpoint was supported by Mine Ayman, who on an interview with Best FM said that the rise in Yener's career happened over a short period of time due to her beautiful voice and good choice of songs.

When she released the album Apayrı in 2006, her image was compared to that of Sibel Kekilli, and hair slightly wavy hairstyle was found similar to that of Madonna's in the late 1970s.

The magazine's editor Uğur Yüksel said that Yener's choice as a gay icon was due to the effective statements that she had made which attracted the favor of homosexuals.

Onur Baştürk from Hürriyet saw the choice for the song's title as an effort to promote Yener outside Turkey through the LGBT movement and criticized the singer by saying, "When it suits your work, 'love wins'.

"[255] In the same period, Yener became the target of criticism from the LGBT movement after images and footage showing the singer İntizar being involved in an intimate relationship with another woman were leaked on the internet.

The company and Yener reacted to the criticism by issuing separate statements and arguing that the contract's termination was not related in any way to İntizar's sexual orientation, and the decision was only made because of the lack of trust between the two parties.

In a statement, Yener said that the party was not cancelled by her but through a warning issued by the production company based on their agreement on naming rights, and added: "I am always full of support and love for LGBT.

[277] In July 2014, Yener and other artists from the same production company joined Prime Minister Recep Tayyip Erdoğan's campaign meeting for the presidential elections.