The Hanwa Expressway (阪和自動車道, Hanwa Jidōsha-dō) is a national expressway in the Kinki region of Japan.

It is owned and operated by West Nippon Expressway Company.

Officially, the route is designated as the Kinki Expressway Matsubara Nachikatsuura Route, however this designation does not appear on any signage.

The expressway is an important route connecting the greater Osaka area with Wakayama, the capital of Wakayama Prefecture.

Beyond Wakayama, the route follows a southerly course parallel to the Pacific Ocean to its terminus with National Route 42 in Tanabe.