Haplogroup L0

In 2014, ancient DNA analysis of a 2,330 year old male forager's skeleton in Southern Africa found that the specimen belonged to the L0d2c1c mtDNA subclade.

This maternal haplogroup is today most closely associated with the Ju, a subgroup of the indigenous San people, which points to population continuity in the region.

[4] In 2016, a Late Iron Age desiccated mummy from the Tuli region in northern Botswana was also found to belong to haplogroup L0.

[10] This illustrates the massive maternal contribution of Khoisan people to sections of the Coloured population of South Africa.

In patients who are given the drug stavudine to treat HIV, Haplogroup L0a2 is associated with a higher likelihood of peripheral neuropathy as a side effect.

The region in Africa where Tishkoff found the greatest level of mitochondrial diversity (green) and the region Behar et al. postulated the most ancient division in the human population began to occur (light brown)
Projected spatial distribution of haplogroup L0 in Africa.
Frequency maps for L0 (total), L0a, L0b, L0d, L0f and L0k
Schematic tree of haplogroup L0. MSA: Middle Stone Age , LSA: Later Stone Age , ka: thousand years ago.