[3] This product only sold about 300 copies, with Rigopulos and Egozy realizing that people, while initially entranced by the game, lost interest after 15 minutes of playing with it.

[2] Harmonix then designed "CamJam", which performed similar functions, this time using simple body gestures to trigger music sequences.

[2][4] This led the two to consider approaching entertainment businesses like Dave & Buster's to include their products, but they soon realized that this would be a year to a year-and-a-half effort, too long for their needs.

They came to a realization that games like karaoke were popular not due to personal expression, but because they encouraged players to try to accurately recreate the songs through their actions.

[2] Harmonix' first major video game was Frequency, with its development funded by Sony Computer Entertainment along with about $2 million in investments in the company.

[5] Featuring songs by a number of underground electronica artists, FreQuency allowed players to perform and remix a variety of music.

Before they left the series, Harmonix had already envisioned expanding the gameplay of Guitar Hero to multiple instruments, a concept that would eventually lead to Rock Band that would develop under MTV.

[10] Shortly after the acquisition by MTV in December 2006, the initial discussion between Dhani Harrison, son of George Harrison, and MTV President Van Toffler occurred that would eventually lead to meetings between Harmonix and Apple Corps, Ltd., leading to the creation of The Beatles: Rock Band, though this was not publicly revealed until late 2008.

As Harmonix's first game as a part of MTV, Rock Band expanded upon the design of Guitar Hero by incorporating three different peripherals: guitar/bass, microphone, and drums.

Harmonix continued to support the game after its initial release by offering a variety of downloadable songs to PlayStation 3 and Xbox 360 players on a weekly basis.

In October 2008, Harmonix, along with MTV Games, announced an exclusive agreement with Apple Corps, Ltd. to produce a standalone title based on the Rock Band premise and featuring the music of The Beatles, to be released late in 2009.

[18] On November 11, 2010, Viacom stated that it was in talks with potential buyers for Harmonix, having already marked the unit as a discontinued operation to write off a $299 million loss for its 2010 third-quarter earnings statement.

[23] Industry analyst Michael Pachter suggested that while Rock Band 3 and Dance Central would generate significant revenue in 2010 holiday sales, Viacom likely made the move to sell Harmonix while the developers were doing well and in the news.

[28][29] According to Peter Kafka of the Wall Street Journal, the sale of Harmonix was heavily discounted, possibly as low as fifty dollars, the equivalent of a fire sale and allowing Viacom to claim certain tax benefits; meanwhile, the new independent owners would assume all ongoing liability for Harmonix' projects, including music licensing fees and unsold inventory.

[32] Shortly after this, Activision announced it was shuttering its Guitar Hero division and cancelling planned games for 2011, which many journalists considered to mark the end of the rhythm game genre; Harmonix's Director of Communications, John Drake, in response to this closure, called the news "discouraging", but affirmed that Harmonix would continue to invest itself in further Rock Band and Dance Central developments for the foreseeable future.

[40] Bloomberg then projected that Harmonix would post $100 million in profit in 2011, based on sales of Dance Central and continued downloadable content for the game.

[41] At the onset of the 2013 E3 conference, Harmonix announced that its next title would be the Kinect-enabled Fantasia: Music Evolved produced in association with Disney Interactive.

[42] In February 2014, Harmonix announced a new title, Chroma, co-developed with Hidden Path Entertainment, which combines their music genre experience with first-person shooters.

The new title, aimed to support backwards compatibility with all previous songs and instrument hardware, was aimed to be more of a platform for the eighth-generation consoles, the PlayStation 4 and Xbox One, as they have no plans to release another standalone title during this console generation but would continually provide free and paid features and content updates throughout its lifetime.

[45] Harmonix had $15 million in investor funding from Spark Capital and Foundry Group to support Rock Band 4, Amplitude and additional projects going forward including virtual reality-based games.

[46][47] In September 2015, Rigopulos announced that he would go to the advisory board for the crowdfunding site Fig, through which Harmonix would obtain funding for its next, yet-announced game.

[48] On 1 March 2016, Harmonix confirmed that the campaign was indeed to raise funds to port Rock Band 4 to the PC, but gamers would only have until 5 April to pledge US$1.5 million to make it happen.

[50] This was revealed in February 2020 as Fuser, a DJ-inspired title to be released for Microsoft Windows, PlayStation 4, Xbox One and Nintendo Switch in late 2020.

Players, as a DJ, interactively mix tracks of popular licensed songs alongside specific rules as they appear on screen.