The family moved often during Fulbright's youth and as a consequence, she spent much of her childhood in Washington, D.C., New York City and Toronto, Ontario, Canada.

In 1987, Mayor served as the Executive Director of the Fulbright Association and moved the headquarters from Bryn Mawr, Pennsylvania to Washington, D.C.

Notable trips included a journey to Japan for the publication of Fulbright's autobiography, Against the Arrogance of Power: My Personal History, Moscow and Germany after the fall of the Berlin Wall and Hawaii.

[4][5] As a result of her status as an international figure of peace and education, she received many awards and honorary degrees.

In 2006, she created the J. William & Harriet Fulbright Center, a nonprofit dedicated to promoting peace through international education and furthering her husband's legacy.