The team is based in Harrisburg, Pennsylvania, and play their home games at FNB Field on City Island, which opened in 1987 and has a seating capacity of 6,187.

The team colors are red, navy blue, gold, and white, the same of the parent club, the Washington Nationals.

The Harrisburg Base Ball Association existed as long ago as 1884 (according to a stock certificate issued on March 1, 1884).

The Senators' reign ended in 1936, when flood waters from the surrounding Susquehanna River ruined their home ballpark, Island Field.

Another team representing Harrisburg affiliated with the Pittsburgh Pirates formed four years later, though in the smaller Interstate League.

The Interstate League disbanded this Harrisburg team in 1952, and any form of professional baseball was not played in the city for the next 35 years.

At the same time, during the mid-1980s, Harrisburg Mayor Stephen Reed initiated a revitalization plan that included a ballpark for a new Minor League Baseball team in the city.

In 1999, the Senators played the Norwich Navigators for a shot at their record-setting fourth consecutive Eastern League championship.

Both caps include the "H" and streaking baseball logo, with the "H" in the same script as the Nationals' pretzel-shaped "W." The white home jerseys include red and navy blue trim around the collar and sleeves with the "Senators" wordmark in red with metallic gold bevels and navy blue outline.

For a time, the Senators remained one of the only sports franchises in the United States to be completely owned by the community in which it was based.

[9] The team was eventually bought by Senators Partners, LLC of Northbrook, Illinois, headed by Jerry Reinsdorf's son Michael, for an Eastern League record $13.25 million.

[10] In April 2024, it was announced that the team had been sold to Diamond Baseball Holdings (DBH), a sports management group owned by Silver Lake, an American private equity firm.

The Ottawa franchise moved to Allentown, Pennsylvania, as the Triple-A team for the Philadelphia Phillies, renamed as the Lehigh Valley IronPigs.

[13] In 2016, the Harrisburg Senators started a tradition by recognizing great players from their history in a unique way, The One & Only World-Famous, Life Size Bobblehead Hall of Fame.

He later was a TV analyst and studio host for the Atlanta Thrashers and then the Columbus Blue Jackets of the National Hockey League.