It also acquired spaces in Berlin, Zurich, New York and Moscow designed by David Adjaye and Caruso St John.

[7] The gallery represented more than 50 artists, including five Turner Prize winners, amongst them Rachel Whiteread, Tony Cragg and Richard Long.

Blain|Southern staged a number of highly praised exhibitions, including Lucian Freud Drawings,[9] Damien Hirst and Felix Gonzalez-Torres: Candy,[10] as well as shows by Bill Viola,[11] Marcel Duchamp[12] and Edward Kienholz.

Blain co-founded Sedition in 2011, establishing the first online marketplace for collectors to buy, share and sell digital artworks.

[20] He had a part in the Wim Wenders film, Palermo Shooting, in which he played an art dealer called Harry, appearing alongside Lou Reed, Dennis Hopper, Milla Jovovich and Peter Lindberhg.