He then appeared in successful Telugu films including Naa Ishtam, Avunu both (2012), Prema Ishq Kaadhal (2013), Anaamika and Maaya (both 2014).

After venturing into Hindi films, Rane has received praise for his portrayal of a gangster in Taish (2020) and an adventure lover in Haseen Dillruba (2021).

Rane was born on 16 December 1983[2][3] in Rajamahendravaram, Andhra State, India to a Telugu mother and a Marathi father.

[24][25] Raja Sen from Hindustan Times said, "Harshvardhan Rane commit fully to his part with noses-flaring and eyebrows furrowing the brow.

"[31] Pallabi Dey Purkayastha of Times of India said, "Rane, as ruthless gangster Pali, is impactful with the exception of his confrontational scene with Samrat.

"[32] Rane portrayed an adventure lover opposite Taapsee Pannu in Haseen Dillruba, a Netflix release.

[33] Anna MM Vetticad stated, "Rane plays the only attention-grabbing character and delivers the film’s only memorable performance.

[35] Post a year hiatus, Rane played a medical student opposite T. J. Bhanu in Dange, his first release of 2024.

[36] Devesh Sharma of Filmfare noted: "Harshvardhan is cast in the mould of the big-hearted college senior and does justice to his role.

"[37] In his next film of the year, Rane played a man convicted in a murder, opposite Divya Khosla Kumar in Savi.

[38] Titas Chowdhury of News18 stated, "Harshvardhan plays Savi’s husband and while he has a limited screen time, he makes sure that you take note of him.

"[39] Later the year, Rane played a local Football player in The Miranda Brothers, alongside Meezaan Jafri and Jeniffer Piccinato.

[46] Priyanka Roy of The Telegraph found him to be "humble, level-headed, easygoing and honest" and added, "Rane impressed with Sanam Teri Kasam and has grabbed attention with Taish and Haseen Dillruba.

[56] He then sold his shirts in Hyderabad from his latest hit Sanam Teri Kasam and managed to single-handedly raise close to Rs Two lakhs and still counting through online sales.

My fans buy my shirts on sale and pose with me holding placards that read Took my #ShirtOff while some choose to simply contribute.