Hartsburg is a village in southern Boone County, Missouri, United States.

The city of Marion in Cole County lies due west across the Missouri River.

Hart Creek flows past the west side of the community.

[5] According to the United States Census Bureau, the village has a total area of 0.21 square miles (0.54 km2), all land.

52.1% of all households were made up of individuals, and 16.7% had someone living alone who was 65 years of age or older.

There were no families and 5.8% of the population living below the poverty line, including no under eighteens and 9.5% of those over 64.

[5] The Hartsburg Pumpkin Festival is held each year on the second Saturday and Sunday of October, which includes games, foods, and crafts.

Each year during the festival tens of thousands come to eat and shop at the numerous venues and food booths.