Grubb made his professional debut with the Greensboro Champs of the Carolina Association in 1909, and had a .180 batting average in 14 games with them.

Grubb spent the 1911 and 1912 seasons with the Morristown Jobbers of the Appalachian League and had a .275 average both years, playing in 97 and 101 games, respectively.

[1] At the end of the season, Grubb was brought onto the Cleveland Naps major league roster.

He did not play in 1918, but returned to Waco in 1919, then joined the Wichita Falls Spudders during the 1920 season.

He spent the final three seasons of his career with the Corsicana Oilers, and served as the team's manager in 1923 as well.