[2] Hattersley was historically a township in the ancient parish of Mottram-in-Longdendale, which formed part of the Macclesfield Hundred of Cheshire.

In some cases, including Mottram-in-Longdendale, the civil functions were exercised by each township separately rather than the parish as a whole.

In 1866, the legal definition of 'parish' was changed to be the areas used for administering the poor laws, and so Hattersley became a civil parish.

The transfer brought a £40 million, seven-year improvement plan for existing housing tied to a £140m investment from a private developer.

Selective demolition has begun to remove some obsolete housing leaving space for redevelopment and investment in education and public services.

The body of Lesley Ann Downey was buried on nearby Saddleworth Moor the day after her murder on Boxing Day 1964, and found there during the initial search of the moors nearly a year later, but the body of Edward Evans was found locked in a bedroom at the house before the couple could dispose of it; the police then went on to find the evidence to link Brady and Hindley to the earlier murders.

[14][15] In October 1987, Manchester City Council demolished the house as they could not find tenants willing to live there.

Many new developments have been important in kick-starting the regeneration of the Hattersley district; these include new housing, a large Tesco Extra superstore and Adventure Longdendale (a trampolining, Laser Quest and play centre).

There are also plans for Hattersley Retail Park; this was originally scheduled to open in 2021, but has faced multiple setbacks.