Heart-hand syndrome, Spanish type, also known as heart-hand syndrome type 3 or III, is a very rare genetic disorder which is characterized by heart, hand, and sometimes feet abnormalities.

Only one family with the disorder has been reported in medical literature.

[3] People with this disorder have symptoms that affect the heart, hands and feet.

These include:[4][5][6] This condition was first discovered by Ruiz de la Fuente et al., when they described a 3-generation family from Spain with the symptoms mentioned above.

The cardiac defects varied between family members; 3 members had intraventicular conduction defects and 1 had a sick sinus.