[2] Mitts was part of the defensive line that helped the Gators win their first-ever NCAA Women's Soccer Championship in 1998.

[5][6] Straight out of college, Mitts played for Tampa Bay Extreme of W-League in 2000 while waiting for the launch of the new Women's United Soccer Association league.

Throughout her Charge career, Mitts appeared in fifty-one games (4,414 minutes) and recorded eight assists over three seasons.

Mitts returned to the W-League in 2005, playing sparingly for Central Florida Krush while splitting her time between the United States Women's National Team.

[citation needed] Upon the introduction of Women's Professional Soccer, Mitts and fellow USWNT players Angela Hucles and Kristine Lilly were allocated to the Boston Breakers on September 16, 2008.

[10] In the inaugural 2009 Women's Professional Soccer season, Mitts appeared in nineteen games (all starts, 1,631 minutes) and added an assist.

[12] In 2013, Mitts was allocated to the Boston Breakers in the new National Women's Soccer League; however, she retired before the start of the season.

[13] Mitts has represented the United States women's national soccer team in over 100 international matches.

She has served as a studio soccer analyst for ABC, ESPN and ESPN2 during the 2003 FIFA Women's World Cup and was a sideline reporter for several MLS broadcasts in 2005.