The village was first mentioned in the 12th century as "Albertus de Essuic", and means "settlement in the shrubbery".

[3] Heeswijk is a stretched out settlement in the valley of brook and dates from the Early Middle Ages.

In 1546, "Het Slotje" was built for the monks as an L-shaped building with a square tower in the corner.

[6] Heeswijk was a separate municipality until 1969, when it merged with the adjacent village of Dinther.

Since 1 January 1994 it has been part of the larger municipality of Bernheze, which comprises Heesch, Heeswijk-Dinther, Loosbroek, Nistelrode and Vorstenbosch.,[7][8]