Heinrich Bernhard Rupp (or Ruppius) (born 22 August 1688 in Giessen, died 7 March 1719 in Jena) was a German botanist.
He first studied medicine in 1704 and met then Johann Jacob Dillenius (1684-1747).
Rupp wrote a flora about plants around Jena and part of Thuringia.
He published the two first parts but his work is finished after his death by Albrecht von Haller (1708-1777).
Carl von Linné (1707-1778) gave tribute to him with the creation of the genus Ruppia of the family Ruppiaceae.