He was a direct descendant of company founder Friedrich Jacob Merck, who had purchased the Engel-Apotheke (Angel Pharmacy) in Darmstadt in 1668.
The pharmacy is still part of Merck KGaA, but the original building was destroyed during World War II in the bombing campaigns, and therefore it is a new construction.
In addition to this he was occupied with research on the chemical constitution of herbal natural material.
From 1838 until 1841 he ran a candle factory and became a member of the town council of Darmstadt in 1828.
As a court consultant he was working on the homicide case of the Mistress of Görlitz in 1850.