[2][3] In 1904 he completed his habilitation, then continued to teach at the university and starting in 1907 was a consultant for Boehringer Ingelheim.

There he was involved in weapons research for instance finding new synthetic routes for mustard gas.

[6][5] In 1941, Wieland isolated the toxin alpha-amanitin, the principal active agent of one of the world's most poisonous mushrooms Amanita phalloides.

[5] Wieland tried successfully to protect people, especially Jewish students, who were "racially burdened" after the Nuremberg Laws.

Students who were expelled because they were "racially burdened" could stay in Heinrich Wieland's group as chemists or as "Gäste des Geheimrats" (guests of the privy councillor).

First to promote research on chemistry, biochemistry, physiology and clinical medicine of lipids and related substances, nowadays the prize is awarded for outstanding research on biologically active molecules and systems in the fields of chemistry, biochemistry, and physiology as well as on their clinical importance.