Heinz body

The presence of Heinz bodies represents damage to hemoglobin and is classically observed in G6PD deficiency, a genetic disorder that causes hemolytic anemia.

In veterinary medicine, Heinz bodies may be seen following the consumption of foods containing thiosulfate and propylene glycol compounds by cats, dogs and certain primates.

The denaturing process is irreversible and the continual elimination of damaged cells leads to Heinz body anemia.

However, recent reports in the veterinary literature of scientifically sound studies have shown that propylene glycol reduces the red blood cell survival time, renders red blood cells more susceptible to oxidative damage, and has other adverse effects in cats consuming the substance at levels found in soft-moist food.

[14] In light of this new data, CVM amended the regulations to expressly prohibit the use of propylene glycol in cat foods.