Helena of Oświęcim (Polish: Helena Oświęcimska; 1478/80 – after 1524), was a Polish princess member of the House of Piast from the Oświęcim branch and ruling Duchess of Karniów since 1506 until 1523.
Helena's father lost his Duchy of Oświęcim in 1456 and the rest of his lands in 1482.
In 1491 her parents were invested with the Duchy of Karniów by the Bohemian King, because Helena's mother was the last representative of the Ducal line, extinct after the death of Duke Jan IV the Elder in 1483.
One year later (in 1493), Helena's parents were dispossessed from Karniów when the King Władysław II Jagiellon bestowed the Duchy to Baron Johann II, Helena's father-in-law.
Johann II died in 1506 and was succeeded by his son George, who also ruled by right of his wife, as the last heir of the Karniów branch of the Piast dynasty.