He founded RSM Marko in 1989, and has been an advisor to Red Bull Racing and its related teams since 2005, winning six World Constructors' Championship titles between 2010 and 2023.

Marko competed in several race series, including 10 Formula One Grands Prix in 1971 and 1972, but scored no World Championship points.

Marko's Formula One graduates have a combined eight World Drivers' Championship titles and 129 Grands Prix between them, with Vettel achieving the first in 2010.

[9] Marko faced scrutiny in September 2023 for his comments regarding Red Bull Racing driver Sergio Pérez's lack of form throughout the 2023 season, following the Italian Grand Prix.

Talking to Red Bull-owned broadcaster ServusTV, he was quoted saying "we know that he has problems in qualifying, he has fluctuations in form, he is South American and he is just not as completely focused in his head as Max Verstappen is, or as Sebastian Vettel".

[11] Marko apologised on 8 September, stating "I was trying to make a point that [Pérez] has fluctuated in his performance this year, but it was wrong to attribute this to his cultural heritage.