Henderson is a village in Knox County, Illinois, United States.

According to the 2010 census, Henderson has a total area of 0.28 square miles (0.73 km2), all land.

[4] As of the census[6] of 2000, there were 319 people, 137 households, and 102 families residing in the village.

There were 145 housing units at an average density of 532.9 per square mile (205.8/km2).

21.2% of all households were made up of individuals, and 4.4% had someone living alone who was 65 years of age or older.