Henderson is a surname of Scottish origin.
In Scottish Gaelic it is rendered MacEanraig (masculine), and NicEanraig (feminine).
The surname Henderson is borne by numerous unrelated families in Scotland.
The Hendersons of Glencoe, a sept of Clan Donald, derive their surname from the Gaelic MacEanruig.
The surname was unknown in England prior to the 17th century and is first mentioned in a marriage document between one of the Borders Hendersons and the daughter of a Carlisle merchant at Hexham.