She tried other occupations, including working as a researcher for radio and television, but finally decided to make a career of writing.
Major wrote scripts for several television series, including La Boîte à surprise [fr] and L'Évangile en papier [fr] and two plays for Théâtre sans fil: Jeux de rêves and La couronne du destin.
She published almost a thousand articles for various magazines,[1] including Châtelaine and Maclean's,[2] and about a hundred children's books in Quebec and France.
In 1978, her television series Les boucaniers d'eau douce [fr] received the Prix des émissions éducatives.
[2] The Prix littéraire Henriette-Major was created in her honour by the publishing house Dominique et Compagnie.