[5] Crossman brought up his idea of using camels for transportation of people and supplies in the newly conquered American Southwest.

[clarification needed] Wayne was chosen to lead an expedition to the Middle East to purchase $30,000 worth of camels.

They then journeyed to Italy and met Grand Duke Leopold II to see his 250 camels that were said to be able to do the work of 1000 horses.

He also commanded Georgia's Quartermaster General, Ira Roe Foster, to immediately provide supplies for the troops, instructing Foster to "proceed personally, or by duly accredited agents, into all parts of the state, and buy 25,000 suits of clothes and 25,000 pairs of shoes[7] for the destitute Ga. troops in the Confederate service.

After being ordered to Manassas, Virginia, Wayne resigned his commission as a brigadier general and he instead just stuck to his duties as adjutant and inspector-general until the end of the war.

In this action, he was unsuccessful in stopping Union forces from crossing the Oconee River in Wilkinson County, GA.[4][9] Wayne died at his home on March 16, 1883.

[10] Wayne received the First Class Gold Medal of Mammal Division by the Société impériale zoologique d'acclimatation of France in 1858 for his introduction of the camel into the United States.