Henry Clay Nelson (May 30, 1835 – March 10, 1893) was a surgeon in the United States Navy during and after the American Civil War.

On March 22, 1877, he married Adelaide Margaretta Nelson (née Thompson), with whom he had a son Francis.

Nelson retired on April 24, 1884, due to ill health and died at the age of 57 on March 10, 1893, in Concord, New Hampshire.

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