He was born at Marazion, 28 January 1767, and commenced the study of medicine by an apprenticeship to James Kempe, a surgeon at Truro, and at the age of twenty-one came to London, when he entered the United Borough Hospitals.
Five years later he began publication of The Medical and Chirurgical Review, a journal which appeared twice each month, of which he was the projector, editor, and almost sole writer, and which he continued until 1807.
Determining to qualify as a physician, he, in 1802, proceeded to Edinburgh for one year, but then transferred himself to Glasgow, where he graduated doctor of medicine, 16 April 1804.
Returning to the metropolis, he established himself at 17 St. Paul's Churchyard, and on 1 October 1804 was admitted a licentiate of the College of Physicians.
He married in 1796, at Walbrook Church, Harriet Matilda, daughter of William Browne of Kirby Street, Hatton Garden, attorney-at-law, by whom he had ten children.