Shortly after he joined an expedition to Egypt and later he became an assistant professor of Egyptology at Yale University.
[1] In 1958 he started working as an assistant curator at the New York Metropolitan Museum of Art, forming a bond with this place that will last for his entire life.
Since the same year until 1970 Fischer was a member of the committee for the salvage of Abu Simbel temples from being submerged by the Lake Nasser following construction of the Aswan Dam: the small temple of Dendur, which was donated to the United States in 1965 as a gratitude for its efforts, was originally intended to be reconstructed on the banks of the Potomac or the Charles River, but Fischer persuaded the presidential committee that such a placement would have exposed the sandstone blocks to excessive degradation, and the temple was reconstructed and exhibited in the Metropolitan Museum since 1978.
In 1970 Fischer was awarded by the museum patron Lila Acheson Wallace, earning a special chair as the curator of Egyptology.
[1] Henry George Fischer died on January 11, 2006, in Newtown Township, Delaware County, Pennsylvania, aged 82.