Henry John Pettypiece (November 11, 1855 – 1942) was an Ontario journalist, businessman and political figure.
He represented Lambton East in the Legislative Assembly of Ontario as a Liberal member from 1898 to 1904.
He was born in Anderdon Township, Lambton County, the son of Anthony Pettypiece, and apprenticed as a printer with the Amherstburg Echo.
Pettypiece served as ticket agent at Forest for the Canadian Pacific Railway.
Pettypiece served on the executive of the Canadian Free Press Association and was selected as president in 1903.