Henry Lewis Darwin (December 21, 1886 — February 6, 1945) was a Texas Democratic politician that served in the Texas Senate.

On December 21, 1886, Henry Lewis Darwin was born in Delta County, Texas.

He was a staunch supporter of the University of Texas.

He died on February 6, 1945, and is buried in Cooper, Texas.

[1] During the 33rd Texas legislature (1913−1917), Darwin represented Texas Senate district 2, which was composed of Fannin County and Lamar County.