[1] Henry was born at Clifton, Nottingham, where his father rebuilt the Rectory, in 1832.
Henry Spencer Markham (1805-1844), Rector of St. Mary's Church, Clifton and Prebendary of York, and his wife Sophia Charlotte Kaye (a daughter of Sir John Lister Kaye, 1st Baronet).
[2] Henry was educated at Harrow School and Christ Church, Oxford.
In the same year he assumed the surname and arms of Clifton in place of Markham by Royal Licence.
[2] At his death, the Clifton estates passed to his second cousin, Sir Hervey Juckes Lloyd Bruce, 4th Baronet.