In 1855 his health gave way, and during next five years he spent time on visits to Egypt, Italy, and the south of France, being frequently ill.[1] In June 1860 Reynolds accepted the post of president of Cheshunt College, where he moved in August, and acted as professor of dogmatic theology, ecclesiastical history, and New Testament exegesis.
In 1869 he received an honorary degree (DD) from the University of Edinburgh, and in the next few years he was engaged on the project of enlarging the Cheshunt College buildings, in celebration of the centenary of the institution.
Other works were:[1] Reynolds edited the Congregational Register for the West Riding of Yorkshire (London) from 1855 to 1857, and undertook in 1884, with Owen Charles Whitehouse, the prophecies of Hosea and Amos in An Old Testament Commentary for English Readers.
With his brother, John Russell Reynolds, he wrote a novel dealing with the intellectual and religious questions of the time, which was published anonymously in 1860 with the title Yes and No.
[1] On 17 December 1840, at Walworth chapel, Reynolds married Louisa Caroline (died 11 October 1895), the only surviving daughter of Silas Palmer of Newbury, Berkshire.