Herbert (Lefty) Karpel (December 27, 1917 – January 24, 1995) was a Major League Baseball pitcher.

Karpel played for the New York Yankees in 1946.

In 2 career games, he had a 0–0 record, with a 10.80 ERA.

Karpel was born in Brooklyn, New York, attended Richmond Hill High School in Queens, New York, died in San Diego, California, and was Jewish.

This biographical article relating to an American baseball pitcher born in the 1910s is a stub.