In 1857 married Anna Maria Patrick, the niece of Des Moines' founding father, Thomas Mitchell, who in around 1844 became Polk County's first permanent English-speaking settler, its first sheriff and later a state legislator.
[6] During the war, Hoxie's influence within the party and in state politics increased as he allied himself with Republican power players such as James W. Grimes, William B. Allison, John A. Kasson and Grenville M. Dodge.
Hoxie believed that Dodge possessed "a kind of general supervision of affairs civil and military in the state."
"[8] With the war coming to an end, Hoxie and Dodge used their positions to advance the causes of the Union Pacific Railroad and Thomas Durant.
[9] Chief Engineer Peter Dey resigned over the high price of the contract—he had estimated it to be $27,000 per mile-he considered this to be "another of Durant's schemes.
"[10] Hoxie assigned his contract, at the direction of Durant, to Crédit Mobilier of America and others in exchange for cash, stock and a position in the company, all three of which he received.
Hub Hoxie died from complications from surgery on his kidney stones on November 23, 1886, at the Bradbury Apartment House, Broadway and 40th Street in New York City.