He previously played for the Dolphins, the Gold Coast Titans, the Newcastle Knights, the Brisbane Broncos, and the Canterbury-Bankstown Bulldogs in the National Rugby League (NRL) in Australia.

[2] Ese'ese played his junior rugby league for the Mangere East Hawks and Wests Panthers, before being signed by the Canterbury-Bankstown Bulldogs in 2015.

[11] Late in the year, he signed with the Souths Logan Magpies in the Queensland Cup for 2016, while training with the Brisbane Broncos during the 2016 pre-season.

[19] In round 1 of the 2018 season, Ese'ese made his debut for Newcastle in their 19–18 golden point extra-time win over the Manly Warringah Sea Eagles.

[23] Following the Gold Coast's decision not to extend Ese'ese's contract, former coach from the Brisbane Broncos, Wayne Bennett signed him to the Dolphins for the 2023 NRL season.

[25] In round 5 of the 2023 NRL season, Ese'ese made his club debut for the Dolphins against the St George Illawarra Dragons at WIN Stadium.