Adolph Wilhelm Hermann Kolbe (27 September 1818 – 25 November 1884[1]) was a German chemist and academic, and a major contributor to the birth of modern organic chemistry.

Despite these accomplishments and his training important members of the next generation of chemists (including Zaitsev, Curtius, Beckmann, Graebe, Markovnikov, and others), Kolbe is best remembered for editing the Journal für Praktische Chemie for more than a decade, in which his vituperative essays on Kekulé's structure of benzene, van't Hoff's theory on the origin of chirality and Baeyer's reforms of nomenclature were personally critical and linguistically violent.

A new opportunity arose in 1845, when he became assistant to Lyon Playfair at the new Museum of Economic Geology in London and a close friend of Edward Frankland.

As late as the 1840s, and despite Friedrich Wöhler's synthesis of urea in 1828, some chemists still believed in the doctrine of vitalism, according to which a special life-force was necessary to create "organic" (i.e., in its original meaning, biologically derived) compounds.

A dramatic success came when his theoretical prediction of the existence of secondary and tertiary alcohols was confirmed by the synthesis of the first of these classes of organic molecules.

[10] In addition to his own bench research and scholarly and editorial work, Kolbe oversaw student research at Leipzig and especially at Marburg; students spending time under his tutelage included Peter Griess, Aleksandr Mikhailovich Zaitsev (known for Zaitsev's rule predicting the product composition of elimination reactions), Theodor Curtius (discoverer of diazo compounds, hydrazines, and the Curtius rearrangement), Ernst Otto Beckmann (discoverer of the Beckmann rearrangement), Carl Graebe (discoverer of alizarin), Oscar Loew, Constantin Fahlberg, Nikolai Menshutkin, Vladimir Markovnikov (first to describe carbocycles smaller and larger than cyclohexane, and known for Markovnikov's rule describing addition reactions to alkenes), Jacob Volhard, Ludwig Mond, Alexander Crum Brown (first to describe the double bond of ethylene), Maxwell Simpson, and Frederick Guthrie.

van't Hoff, and the reform of chemical nomenclature by Adolf von Baeyer, was expressed in his vituperative articles in the Journal für Praktische Chemie.